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Induction of labor by prostaglandin E 2 in relation to the Bishop score
Author(s) -
Kemp B,
Winkler M,
Rath W
Publication year - 2000
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/s0020-7292(00)00253-8
Subject(s) - medicine , bishop score , cervix , prostaglandin , prostaglandin e2 , labor induction , induction of labor , randomized controlled trial , gynecology , intravaginal administration , obstetrics , oxytocin , vagina , pregnancy , surgery , cancer , biology , genetics
Objective : To compare the effectiveness of prostaglandin E 2 intravaginal gel with the intracervical gel in patients with an unfavorable cervix. Method : In a prospective multicenter trial 470 patients with unfavorable Bishop scores (3–4) were randomized to receive prostaglandin vaginal gel (2 mg) or intracervical gel (0.5 mg). Results : In patients with unfavorable Bishop scores the intravaginal application route resulted in a better cervical ripening, a shorter induction to delivery interval and a higher cumulative rate of deliveries during 24 h ( P =0.01). Conclusion : Intravaginal instillation of prostaglandin E 2 gel for induction of labor is effective in patients with an unfavorable Bishop score of 3–4.