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Kinetics of peroxidases in guinea pig bone marrow under immunostimulation
Author(s) -
Keyhani E,
Zarei M.A,
Lashgarblooki-Livani T
Publication year - 1999
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/s0014-5793(99)00665-1
Subject(s) - eosinophil peroxidase , myeloperoxidase , peroxidase , bone marrow , guinea pig , isozyme , eosinophil , biology , immunology , chemistry , enzyme , microbiology and biotechnology , biochemistry , endocrinology , inflammation , asthma
Eosinophil peroxidase and myeloperoxidase play an important role in the host defense. Both enzymes are present in bone marrow, synthesized by blood progenitor cells. This research investigated the kinetic properties of peroxidases under immunostimulation in guinea pig bone marrow. Results suggest that there are at least two myeloperoxidase isozymes and at least three eosinophil peroxidase isozymes in guinea pig bone marrow and that some of these isozymes are expressed upon immunostimulation.