Premium
Micellar catalysis for oxidation of nitric oxide (NO) in the multi‐phase systems in vivo
Author(s) -
Beda Nataliya V.,
Suntsova Tatiana P.
Publication year - 1999
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/s0014-5793(99)00578-5
Subject(s) - reagent , catalysis , chemistry , phase (matter) , micelle , aqueous solution , aqueous two phase system , partition (number theory) , realization (probability) , volume fraction , partition coefficient , thermodynamics , organic chemistry , physics , mathematics , statistics , combinatorics
The equation of the dependence of the third‐order reaction acceleration due to concentrating the reagents in a small volume of the hydrophobic phase on the partition coefficients of reagents ( Q ) and on the lipophilic phase fraction ( x ), [ k app / k 2 = H ( Q NO , Q O2 , x )] was analyzed. It was demonstrated that the numeric value of d H /d x at x →0 could not be used in order to calculate the efficiency of catalysis from the experimental data. It was shown that, unlike in two‐phase systems (with an aqueous and a hydrophobic phase), the dependence of H on Q in multi‐phase systems, that include all in vivo systems, is different. The multiple phase state of the systems has a determining role for a regulation of NO‐dependent processes and in the realization of conditions of ‘NO catastrophes’.