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Repression of enzymes of the pentose phosphate pathway by glucose in fission yeast
Author(s) -
Mehta Shwetal,
Velmurugan S,
Lobo Zita
Publication year - 1998
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/s0014-5793(98)01420-3
Subject(s) - pentose phosphate pathway , schizosaccharomyces pombe , yeast , enzyme , biochemistry , fission , psychological repression , chemistry , pentose , glycerol , ethanol , biology , saccharomyces cerevisiae , glycolysis , gene , gene expression , fermentation , physics , quantum mechanics , neutron
We examine here the effect of carbon sources on the synthesis of the shunt pathway enzymes in the fission yeast Schizosaccharomyces pombe growing on a mixture of ethanol and glycerol. δ‐Gluconolactone induces practically every one of these enzymes. Glucose in contrast tends to attenuate the synthesis of the majority of them. RNA analysis confirms that their induction and repression reflect changes in the levels of their transcripts.