Premium
A structural tree for proteins containing S‐like β‐sheets
Author(s) -
Efimov Alexander V
Publication year - 1998
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/s0014-5793(98)01244-7
Subject(s) - tree (set theory) , chemistry , computational biology , combinatorics , mathematics , biology
A structural tree for proteins and domains containing S‐like β‐sheets has been constructed. An S‐like β‐sheet is taken as a starting structure in modelling or as a root structure of the tree. Larger structures are obtained by a stepwise addition of β‐strands and/or α‐helices to the root S‐like β‐sheet in accordance with a restricted set of rules inferred from known principles of protein structure. Applications of the structural tree to structure comparison, protein classification and protein folding are described.