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Measuring elasticity of biological materials by atomic force microscopy
Author(s) -
Vinckier Anja,
Semenza Giorgio
Publication year - 1998
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/s0014-5793(98)00592-4
Subject(s) - atomic force microscopy , elasticity (physics) , biological materials , nanotechnology , microscopy , materials science , chemistry , physics , biochemical engineering , engineering , optics , composite material
Atomic force microscopy (AFM) has proved its value not only for resolving the topographical structure of biological samples, but also for probing inherent properties of biological structures, like local interaction forces, mechanical properties or dynamics in a natural (physiological) environment. This minireview focuses on the acquisition of elasticity data of biomaterials by AFM. A possible theoretical model is presented, followed by a practical `how to do it with AFM', and, finally, a brief overview of publications in this field is given.