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Carotenoid mixtures protect multilamellar liposomes against oxidative damage: synergistic effects of lycopene and lutein
Author(s) -
Stahl Wilhelm,
Junghans Angelika,
de Boer Ben,
Driomina Elena S,
Briviba Karlis,
Sies Helmut
Publication year - 1998
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/s0014-5793(98)00434-7
Subject(s) - lutein , carotenoid , zeaxanthin , lycopene , chemistry , antioxidant , thiobarbituric acid , food science , xanthophyll , beta carotene , biochemistry , lipid peroxidation
Antioxidant activity of carotenoids in multilamellar liposomes assayed by inhibition of formation of thiobarbituric acid‐reactive substances was in the ranking: lycopene>α‐tocopherol>α‐carotene>β‐cryptoxanthin>zeaxanthin=β‐carotene>lutein. Mixtures of carotenoids were more effective than the single compounds. This synergistic effect was most pronounced when lycopene or lutein was present. The superior protection of mixtures may be related to specific positioning of different carotenoids in membranes.