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Involvement of ecto‐ATPase and extracellular ATP in polymorphonuclear granulocyte‐endothelial interactions
Author(s) -
Sud'ina Galina F,
Mirzoeva Olga K,
Galkina Svetlana I,
Pushkareva Marina A,
Ullrich Volker
Publication year - 1998
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/s0014-5793(98)00102-1
Subject(s) - microbiology and biotechnology , granulocyte , atpase , endothelium , extracellular , chemistry , receptor , adhesion , biochemistry , enzyme , immunology , biology , endocrinology , organic chemistry
We conclude that PMN‐endothelial adhesion is counteracted by an ecto‐ATPase or by ATP receptors with ATPase activity. Such interactions may play a role in PMN rolling and diapedesis as well as in the pathophysiology of PMN activation by an anergic endothelium.