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Expression of the putative membrane fatty acid transporter (FAT) in taste buds of the circumvallate papillae in rats
Author(s) -
Tsutomu Fukuwatari,
Teruo Kawada,
Masashi Tsuruta,
Takehisa Hiraoka,
Toshihiko Iwanaga,
Etsuro Sugimoto,
Tohru Fushiki
Publication year - 1997
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/s0014-5793(97)01055-7
Subject(s) - lingual papilla , immunohistochemistry , taste , tongue , adipose tissue , taste bud , messenger rna , biology , chemistry , biochemistry , gene , pathology , medicine , immunology
The putative membrane fatty acid transporter (FAT) protein and its mRNA, originally expressed in adipose tissue, were found in the tongue of rats. Northern blot analysis showed a significant expression of FAT mRNA in the epithelial layer of circumvallate papillae. Immunohistochemical staining revealed that immunoreactivity for FAT is specifically localized in the apical part of taste bud cells, possibly gustatory cells, in the circumvallate papillae.