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Detection of specific IgE to human milk proteins in sera of atopic infants
Author(s) -
Cantisani Annamaria,
Giuffrida Maria Gabriella,
Fabris Claudio,
Bertino Enrico,
Coscia Alessandra,
Oggero Roberto,
Monti Giovanna,
Stroppiana Paola,
Conti Amedeo
Publication year - 1997
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/s0014-5793(97)00828-4
Subject(s) - immunoglobulin e , immunology , chemistry , biology , antibody
Specific IgE (sIgE) for cow's milk proteins (CMP) have been reported to be present in blood sera of exclusively breast‐fed infants. The aim of this study was to find whether the presence of sIgE to human milk proteins in the sera of exclusively breast‐fed infants could explain the apparent detection of sIgE to CMP in infants that were never previously in contact with cow's milk. sIgE for human milk whey proteins were found in the blood sera of atopic infants, and these sIgE strongly cross‐reacted with the corresponding CMP. In none of the sera examined were sIgE to bovine β‐lactoglobulin detected.