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Differential effects of five types of antipathogenic plant peptides on model membranes
Author(s) -
Caaveiro José Manuel M,
Molina Antonio,
González-Mañas Juan M,
Rodrı́guez-Palenzuela Pablo,
Garcı́a-Olmedo Francisco,
Goñi Félix M
Publication year - 1997
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/s0014-5793(97)00613-3
Subject(s) - vesicle , liposome , defensin , chemistry , membrane , biochemistry , peptide , phospholipid , biophysics , biology
The effects of five antipathogenic plant peptides, wheat α‐thionin, potato PTH1 defensin, barley LTP2 lipid transfer protein, and potato tuber DL1 and DL2 defensins, have been tested against phospholipid vesicles (liposomes). Wheat thionin very actively induces aggregation and leakage of negatively charged vesicles. LTP2 displays the same activities, although to a limited extent. Under certain conditions PTH1 and DL2 induce vesicle aggregation, but not leakage. Potato defensin DL1 failed to show any effect on liposomes. The same peptides have been assayed against a plant pathogenic bacterium, both the membrane‐active and ‐inactive compounds having efficient antibacterial action.