Premium
Macropexophagy in Hansenula polymorpha : facts and views
Author(s) -
Kiel Jan A.K.W,
Komduur Janet A,
van der Klei Ida J,
Veenhuis Marten
Publication year - 2003
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/s0014-5793(03)00794-4
Subject(s) - organelle , compartmentalization (fire protection) , peroxisome , yeast , microbiology and biotechnology , biology , function (biology) , homeostasis , compartment (ship) , model organism , biochemistry , enzyme , gene , oceanography , geology
The hallmark of eukaryotic cells is compartmentalization of distinct cellular functions into specific organelles. This necessitates the cells to run energetically costly mechanisms to precisely control maintenance and function of these compartments. One of these continuously controls organelle activity and abundance, a process termed homeostasis. Yeast peroxisomes are favorable model systems for studies of organelle homeostasis because both the proliferation and degradation of these organelles can be readily manipulated. Here, we highlight recent achievements in regulation of peroxisome turnover in yeast, in particular Hansenula polymorpha , with a focus on directions of future research.