Premium
Serine (threonine) phosphatase(s) acting on cAMP‐dependent phosphoproteins in mammalian mitochondria
Author(s) -
Signorile Anna,
Sardanelli Anna Maria,
Nuzzi Rosanna,
Papa Sergio
Publication year - 2002
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/s0014-5793(02)02226-3
Subject(s) - serine , phosphatase , threonine , protein phosphatase 2 , biochemistry , phosphorylation , mitochondrion , inner membrane , chemistry , dusp6 , microbiology and biotechnology , membrane , biology
Immunochemical and functional evidence showing the existence in the inner membrane and matrix fraction of mammalian mitochondria of serine/threonine phosphatases acting on cAMP‐dependent phosphoproteins is presented. Mg 2+ ‐dependent Ca 2+ ‐inhibitable PP2C phosphatase, associated to the inner membrane, dephosphorylates the 18 kDa (NDUFS4 gene) of complex I.