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Normalization of nomenclature for peptide motifs as ligands of modular protein domains
Author(s) -
Aasland Rein,
Abrams Charles,
Ampe Christophe,
Ball Linda J.,
Bedford Mark T.,
Cesareni Gianni,
Gimona Mario,
Hurley James H.,
Jarchau Thomas,
Lehto Veli-Pekka,
Lemmon Mark A.,
Linding Rune,
Mayer Bruce J.,
Nagai Makoto,
Sudol Marius,
Walter Ulrich,
Winder Steve J.
Publication year - 2002
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/s0014-5793(01)03295-1
Subject(s) - normalization (sociology) , nomenclature , computer science , modular design , parsing , computational biology , biology , artificial intelligence , programming language , taxonomy (biology) , botany , sociology , anthropology
We propose a normalization of symbols and terms used to describe, accurately and succinctly, the detailed interactions between amino acid residues of pairs of interacting proteins at protein:protein (or protein:peptide) interfaces. Our aim is to unify several diverse descriptions currently in use in order to facilitate communication in the rapidly progressing field of signaling by protein domains. In order for the nomenclature to be convenient and widely used, we also suggest a parallel set of symbols restricted to the ASCII format allowing accurate parsing of the nomenclature to a computer‐readable form. This proposal will be reviewed in the future and will therefore be open for the inclusion of new rules, modifications and changes.