Premium
Recent developments and future directions in computational genomics
Author(s) -
Tsoka Sophia,
Ouzounis Christos A
Publication year - 2000
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/s0014-5793(00)01776-2
Subject(s) - genomics , context (archaeology) , computational genomics , computational biology , computer science , representation (politics) , structural genomics , genome , data science , field (mathematics) , exploit , computational model , sequence (biology) , biology , artificial intelligence , genetics , mathematics , protein structure , gene , paleontology , biochemistry , computer security , politics , political science , pure mathematics , law
Computational genomics is a subfield of computational biology that deals with the analysis of entire genome sequences. Transcending the boundaries of classical sequence analysis, computational genomics exploits the inherent properties of entire genomes by modelling them as systems. We review recent developments in the field, discuss in some detail a number of novel approaches that take into account the genomic context and argue that progress will be made by novel knowledge representation and simulation technologies.