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Silefrin, a sodefrin‐like pheromone in the abdominal gland of the sword‐tailed newt, Cynops ensicauda
Author(s) -
Yamamoto Kazutoshi,
Kawai Yuka,
Hayashi Tomoko,
Ohe Yoshihide,
Hayashi Hiroaki,
Toyoda Fumiyo,
Kawahara Genri,
Iwata Takeo,
Kikuyama Sakaé
Publication year - 2000
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/s0014-5793(00)01455-1
Subject(s) - pheromone , sword , zoology , sex pheromone , biology , endocrinology , anatomy , ecology , computer science , world wide web
Sodefrin‐like female‐attracting pheromone was purified from the abdominal glands of male sword‐tailed newts, Cynops ensicauda , by gel‐filtration chromatography and reversed‐phase high‐performance liquid chromatography. The final product comprises 10 amino acid residues with the sequence SILSKDAQLK which coincided with the sequence deduced from its precursor cDNA. This peptide was designated silefrin. The sequence of silefrin was different from that of sodefrin by two amino acid residues, with substitutions Leu for Pro and Gln for Leu at positions 3 and 8, respectively. Both native and synthetic silefrin exerted an equipotent activity in attracting conspecific females.