Fibrinolysis shut down in COVID-19 patients: Report on two severe cases with potential diagnostic and clinical relevance | Zendy

Tamam Bakchoul | Zendy; Stefanie Hammer | Zendy; Peter Lang | Zendy; Peter Rosenberger | Zendy

Open Access

Fibrinolysis shut down in COVID-19 patients: Report on two severe cases with potential diagnostic and clinical relevance

Author(s) -

Tamam Bakchoul,

Stefanie Hammer,

Peter Lang,

Peter Rosenberger

Publication year - 2020

Publication title -

thrombosis update

Language(s) - English

Resource type - Journals

ISSN - 2666-5727

DOI - 10.1016/j.tru.2020.100008

Subject(s) - fibrinolysis , covid-19 , coagulopathy , medicine , intensive care medicine , coagulation , factor xii , immunology , virology , disease , infectious disease (medical specialty) , outbreak

Highlights •To date most reports on COVID-19 associated coagulopathy focused an increased activation of the plasmatic coagulation system. •Using a novel method to assess clot lysis we observed abnormalities in fibrinolysis in COVID-19 infection. •Our finding suggests that fibrinolysis system may contribute to the procoagulatory status in COVID-19 patients.

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