Open AccessEndocrinologic management of hyperthyroidism and the impact on thyroid eye disease
Author(s) -
Fatemeh Rajaii,
Shivani Gupta,
Raymond S. Douglas
Publication year - 2014
Publication title -
taiwan journal of ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.519
H-Index - 9
eISSN - 2211-5072
pISSN - 2211-5056
DOI - 10.1016/j.tjo.2014.03.001
Subject(s) - medicine , antithyroid drugs , disease , radioactive iodine , thyroid , graves' disease , thyroidectomy , pediatrics , intensive care medicine
AbstractThyroid eye disease (TED) is a complex inflammatory disease with a poorly understood etiopathogenesis. It is often, but not always, associated with Graves' disease and the endocrinologic manifestations of hyperthyroidism. Controversy exists regarding optimal treatment of hyperthyroidism especially with regard to the progression of orbitopathy. We review the literature examining the effectiveness of antithyroid drugs, radioactive iodine, and thyroidectomy for long-term endocrinologic management, and their effect on the progression of TED. In formulating an individualized treatment plan, considerations include rates of recurrent hyperthyroidism, treatment-associated complications, and effect on TED progression