Open AccessSarcoidosis with uveitis occurring in Taiwanese sisters
Author(s) -
Li-Tzu Yang,
Yu-Mei Chung,
ShuiMei Lee,
Wen-Jing Hsu,
YiChen Yeh
Publication year - 2013
Publication title -
taiwan journal of ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.519
H-Index - 9
eISSN - 2211-5072
pISSN - 2211-5056
DOI - 10.1016/j.tjo.2012.06.001
Subject(s) - sarcoidosis , medicine , uveitis , biopsy , dermatology , pathology , ophthalmology
arcoidosis is a multisystem granulomatous inflammatory disease, and uveitis is the most common ocular manifestation. Herein we report a female sibling pair both having sarcoidosis with uveitis. A 59-year-old woman presented with chronic panuveitis in both eyes lasting for one year. Enlarged mediastinal lymph nodes were demonstrated on computed tomography, and mediastinoscopic biopsy revealed chronic non-caseating granulomatous inflammation. Sarcoidosis was diagnosed. Eight months later, her younger sister developed bilateral anterior and intermediate uveitis. She was also diagnosed with sarcoidosis confirmed by intrathoracic lymph node biopsy. This is the first report of familial sarcoidosis presented with uveitis in Taiwan