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Ocular metastasis of lung adenocarcinoma with ELM4-ALK translocation: A case report with a review of the literature
Author(s) -
Kailun Jiang,
Seymour Brownstein,
Harmanjatinder S. Sekhon,
Scott A. Laurie,
Kay Lam,
Steven Gilberg,
William A. Britton
Publication year - 2013
Publication title -
saudi journal of ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.359
H-Index - 25
eISSN - 2542-6680
pISSN - 1319-4534
DOI - 10.1016/j.sjopt.2013.06.011
Subject(s) - medicine , malignancy , adenocarcinoma , presentation (obstetrics) , choroid , lung , pulmonary adenocarcinoma , pathology , metastasis , radiology , cancer , retina , physics , optics
Choroidal metastasis is the most common intraocular neoplasm and is associated with significant morbidity. In a small percentage of patients, ocular manifestation may be the initial presentation of a systemic malignancy and can be diagnostically difficult to distinguish from ocular primary malignancies. Herein, we present a case of a never-smoker whose ocular pathology was integral to the diagnosis and management of a lung adenocarcinoma harboring a rare oncogene. Through this case, we have explored important diagnostic and therapeutic considerations of pulmonary metastases to the choroid.

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