Open AccessIonic liquid 1-butyl-3-methylimidazolium bromide ([Bmim]Br) as a green and neutral reaction media for the catalyst-free synthesis of 1-amidoalkyl-2-naphthols
Author(s) -
Abdolkarim Zare,
Alireza Hasaninejad,
Alireza Salimi Beni,
Ahmad Reza MoosaviZare,
Maria Merajoddin,
E. Kamali,
M. Akbari-Seddigh,
Zahra Parsaee
Publication year - 2011
Publication title -
scientia iranica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.299
H-Index - 51
eISSN - 2345-3605
pISSN - 1026-3098
DOI - 10.1016/j.scient.2011.05.005
Subject(s) - ionic liquid , bromide , catalysis , chemistry , condensation , urea , acetamide , organic chemistry , condensation reaction , green chemistry , inorganic chemistry , medicinal chemistry , physics , thermodynamics
An efficient and simple new method for the preparation of 1-amidoalkyl-2-naphthols as biologically interesting compounds is described. The one-pot multi-component condensation of β-naphthol, aromatic aldehydes and acetamide/urea in ionic liquid 1-butyl-3-methylimidazolium bromide ([Bmim]Br) under microwave and catalyst-free conditions affords the title compounds at high yields and in short reaction times