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Epigenética en enfermedades alérgicas y asma
Author(s) -
José A. CastroRodríguez,
Bernardo J. Krause,
Ricardo Uauy,
Paola Casanello
Publication year - 2016
Publication title -
revista chilena de pediatría
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.241
H-Index - 16
eISSN - 0717-6228
pISSN - 0370-4106
DOI - 10.1016/j.rchipe.2016.02.006
Subject(s) - medicine , asthma , humanities , immunology , philosophy
Allergic diseases and asthma are the result of complex interactions between genetic predisposition and environmental factors. Asthma is one of the most prevalent chronic disease among children. In this article we review some environmental factors like: allergen exposition, tobacco, bacteria, microbial components, diet, obesity and stress, which influences during intrauterine and infancy life in the epigenetic regulation of asthma and allergic diseases. The review has been done in three models: in-vitro, animal and human.

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