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Prevalence of Bleeding Complications Following Ultrasound‐Guided Botulinum Toxin Injections in Patients on Anticoagulation or Antiplatelet Therapy
Author(s) -
LaVallee Jeffrey,
Royer Regan,
Smith Geoffrey
Publication year - 2017
Publication title -
pmandr
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.617
H-Index - 66
eISSN - 1934-1563
pISSN - 1934-1482
DOI - 10.1016/j.pmrj.2017.06.002
Subject(s) - medicine , surgery , rivaroxaban , complication , stroke (engine) , hematoma , anesthesia , warfarin , atrial fibrillation , mechanical engineering , engineering
Background Patients receiving anticoagulation or antiplatelet therapy may be at higher risk for bleeding complications following intramuscular chemodenervation injections. Musculoskeletal ultrasound may be able to reduce the risk of bleeding complications by providing real‐time visualization of vascular structures and postinjection monitoring. Limited data exist addressing the risk of bleeding complications following ultrasound‐guided botulinum neurotoxin intramuscular chemodenervation procedures in the setting of anticoagulation or antiplatelet therapy. Objective To provide initial outcome data regarding bleeding complications in patients on anticoagulation or antiplatelet therapy who have received ultrasound‐guided botulinum neurotoxin intramuscular chemodenervation procedures. Design Retrospective, medical record review. Setting Academic institution outpatient spasticity clinic. Participants Total of 328 ultrasound‐guided intramuscular botulinum toxin injections performed in 15 patients (mean age 53.8 years) with the predominant indication for chemodenervation being spastic paresis secondary to stroke. Methods The medical records of all patients undergoing ultrasound‐guided intramuscular chemodenervation procedures performed between July 1, 2011, and October 16, 2015, were reviewed for demographic information, details regarding anticoagulation therapy, procedure specifics, and postinjection bleeding complications. All patients had a postinjection ultrasound to screen for hematoma. Main Outcome Measures Prevalence of clinically significant bleeding complications and of sonographically documented subclinical bleeding complications following ultrasound‐guided chemodenervation procedures in patients on anticoagulation or antiplatelet therapy. Results Of 328 procedures, only 2 subclinical hematomas were detected, resulting in a bleeding complication rate of 0.61% in this patient population. The target muscles in these cases were tibialis posterior and pronator teres, and both cases were in patients on anticoagulation therapy (as opposed to antiplatelet therapy). Conclusions The risk of clinically significant bleeding complication appears to be very small following ultrasound‐guided intramuscular chemodenervation procedures in the setting of systemic anticoagulation or antiplatelet therapy. Level of Evidence IV