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Biologic and Plastic Effects of Experimental Traumatic Brain Injury Treatment Paradigms and Their Relevance to Clinical Rehabilitation
Author(s) -
Garcia Alexandra N.,
Shah Mansi A.,
Dixon C. Edward,
Wagner Amy K.,
Kline Anthony E.
Publication year - 2011
Publication title -
pmandr
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.617
H-Index - 66
eISSN - 1934-1563
pISSN - 1934-1482
DOI - 10.1016/j.pmrj.2011.03.017
Subject(s) - traumatic brain injury , neuroplasticity , medicine , rehabilitation , physical medicine and rehabilitation , psychological intervention , affect (linguistics) , physical therapy , neuroscience , psychology , psychiatry , communication
Neuroplastic changes, whether induced by traumatic brain injury (TBI) or therapeutic interventions, alter neurobehavioral outcome. Here we present several treatment strategies that have been evaluated by using experimental TBI models and discuss potential mechanisms of action (ie, plasticity) and how such changes affect function.