Epidemics of Norovirus GII.4 Variant in Outbreak Cases in Korea, 2004–2012 | Zendy

Sunyoung Jung | Zendy; Hyun Ju Jeong | Zendy; Bo-Mi Hwang | Zendy; CheonKwon Yoo | Zendy; Gyung Tae Chung | Zendy; Hyesook Jeong | Zendy; Yeon-Ho Kang | Zendy; DeogYong Lee | Zendy

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Epidemics of Norovirus GII.4 Variant in Outbreak Cases in Korea, 2004–2012

Author(s) -

Sunyoung Jung,

Hyun Ju Jeong,

Bo-Mi Hwang,

CheonKwon Yoo,

Gyung Tae Chung,

Hyesook Jeong,

Yeon-Ho Kang,

DeogYong Lee

Publication year - 2015

Publication title -

osong public health and research perspectives

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.357

H-Index - 24

eISSN - 2233-6052

pISSN - 2210-9099

DOI - 10.1016/j.phrp.2015.10.002

Subject(s) - outbreak , norovirus , virology , phylogenetic tree , polymerase chain reaction , biology , sequence (biology) , genetics , gene

Norovirus GII.4 is recognized as a worldwide cause of nonbacterial outbreaks. In particular, the GII.4 variant occurs every 2-3 years according to antigenic variation. The aim of our study was to identify GII.4 variants in outbreaks in Korea during 2004-2012. Partial VP1 sequence of norovirus GII.4-related outbreaks during 2004-2012 was analyzed. The partial VP1 sequence was detected with reverse transcription-polymerase chain reaction, seminested polymerase chain reaction, and nucleotide sequence of 312-314 base pairs for phylogenetic comparison. Nine variants emerged in outbreaks, with the Sydney variant showing predominance recently. This predominance may persist for at least 3 years, although new variants may appear in Korea.

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