Open AccessIdentification of genetic modifiers of somatic CAG instability in Huntington's Disease by in vivo CRISPR – Cas9 genome editing
Author(s) -
Ana Azevedo,
Marina Kovalenko,
Marissa A Andrew,
F. Zhang,
J. Lee,
Vanessa C. Wheeler,
Mouro R. Pinto
Publication year - 2017
Publication title -
porto biomedical journal/porto biomedical journal
Language(s) - English
Resource type - Journals
eISSN - 2444-8672
pISSN - 2444-8664
DOI - 10.1016/j.pbj.2017.07.083
Subject(s) - huntingtin , trinucleotide repeat expansion , crispr , somatic cell , huntington's disease , biology , genetics , genome editing , huntingtin protein , gene knockin , disease , allele , gene , mutant , medicine , pathology