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Evaluation of muscle metabolic activity in the lower limb of a transfemoral amputee using a prosthesis by using 18 F‐FDG PET imaging—an application of PET imaging to rehabilitation
Author(s) -
Shinozaki Tetsuya,
Suzuki Keiko,
Yamaji Takehiko,
Ichikawa Akihiro,
Inoue Tomio,
Takagishi Kenji,
Endo Keigo
Publication year - 2004
Publication title -
journal of orthopaedic research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.041
H-Index - 155
eISSN - 1554-527X
pISSN - 0736-0266
DOI - 10.1016/j.orthres.2003.10.018
Subject(s) - medius , volunteer , medicine , prosthesis , gait , lower limb , physical medicine and rehabilitation , metabolic activity , nuclear medicine , anatomy , surgery , physiology , biology , agronomy
This study used FDG PET to evaluate the lower limb muscles metabolic activities of transfemoral amputees during walking with prostheses. As a preliminary study, FDG PET was applied for two normal adult volunteers to evaluate muscle activity in the lower extremities after gait exercise. This same method was applied for two amputee volunteers with prostheses. We found that FDG accumulated more in both gluteus medius muscles after gait exercise compared to other muscles in normal adult volunteers. In the skilled amputee volunteer, FDG uptake increased in the adductor and gluteus medius in the amputated side, while in the unskilled the adductor, gluteus maximus, and gluteus medius showed increased FDG uptake only in the normal side. This result suggests that basic metabolic changes such as an increase in oxidative metabolism and less reliance on glycolytic activity would occur as a result of skeletal muscle training in amputees. © 2003 Orthopaedic Research Society. Published by Elsevier Ltd. All rights reserved.