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Progressive multifocal leukoencephalopathy lesion and brain parenchymal segmentation from MRI using serial deep convolutional neural networks
Author(s) -
Omar AlLouzi,
Snehashis Roy,
Ikesinachi Osuorah,
Prasanna Parvathaneni,
Bryan Smith,
Joan Ohayon,
Pascal Sati,
Dzung L. Pham,
Steven Jacobson,
Avindra Nath,
Daniel S. Reich,
Irene Cortese
Publication year - 2020
Publication title -
neuroimage clinical
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.772
H-Index - 68
ISSN - 2213-1582
DOI - 10.1016/j.nicl.2020.102499
Subject(s) - convolutional neural network , segmentation , progressive multifocal leukoencephalopathy , lesion , computer science , atrophy , artificial intelligence , medicine , deep learning , feature (linguistics) , pattern recognition (psychology) , pathology , multiple sclerosis , linguistics , philosophy , psychiatry
Highlights • PML has characteristic dynamic changes in brain and lesion volume on MRI.• JCnet is an automated method for brain atrophy and lesion segmentation in PML.• JCnet improves PML lesion segmentation accuracy compared to conventional methods.• JCnet can accurately track PML lesion changes over time.

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