Age-dependent cut-offs for pathological deep gray matter and thalamic volume loss using Jacobian integration | Zendy

Roland Opfer | Zendy; Julia Krüger | Zendy; Lothar Spies | Zendy; Marco Hamann | Zendy; Carla A. Wicki | Zendy; Hagen H. Kitzler | Zendy; Carola Gocke | Zendy; Diego Augusto Santos Silva | Zendy; Sven Schippling | Zendy

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Age-dependent cut-offs for pathological deep gray matter and thalamic volume loss using Jacobian integration

Author(s) -

Roland Opfer,

Julia Krüger,

Lothar Spies,

Marco Hamann,

Carla A. Wicki,

Hagen H. Kitzler,

Carola Gocke,

Diego Augusto Santos Silva,

Sven Schippling

Publication year - 2020

Publication title -

neuroimage clinical

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.772

H-Index - 68

ISSN - 2213-1582

DOI - 10.1016/j.nicl.2020.102478

Subject(s) - percentile , medicine , nuclear medicine , confidence interval , pathological , mathematics , statistics

Highlights • Longitudinal MRI data of 189 healthy controls and 127 MS patients were analyzed.• Deep gray matter (deep GMVL) thalamic volume loss (ThalaVL) was assessed.• Magnitude of measurement error was estimated by means of 162 MRI scan-rescans.• Age-dependent cut-offs for pathological deep GMVL and ThalaVL are provided.• Result help interpreting deep GMVL and ThalaVL measurements in individual MS patients.

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