CSF enhancement on post-contrast fluid-attenuated inversion recovery images; a systematic review | Zendy

Whitney M. Freeze | Zendy; Merel M. van der Thiel | Zendy; Jeroen de Bresser | Zendy; Catharina J.M. Klijn | Zendy; Ellis S. van Etten | Zendy; Jacobus F.A. Jansen | Zendy; Louise van der Weerd | Zendy; Heidi I.L. Jacobs | Zendy; Walter H. Backes | Zendy; Susanne J. van Veluw | Zendy

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CSF enhancement on post-contrast fluid-attenuated inversion recovery images; a systematic review

Author(s) -

Whitney M. Freeze,

Merel M. van der Thiel,

Jeroen de Bresser,

Catharina J.M. Klijn,

Ellis S. van Etten,

Jacobus F.A. Jansen,

Louise van der Weerd,

Heidi I.L. Jacobs,

Walter H. Backes,

Susanne J. van Veluw

Publication year - 2020

Publication title -

neuroimage clinical

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.772

H-Index - 68

ISSN - 2213-1582

DOI - 10.1016/j.nicl.2020.102456

Subject(s) - medicine , fluid attenuated inversion recovery , cerebrospinal fluid , neuroimaging , etiology , magnetic resonance imaging , radiology , pathology , psychiatry

Highlights• CSF enhancement on post-contrast FLAIR images is a novel marker for BBB leakage. • This neuroradiological marker is frequently observed in neurological diseases. • Post-contrast FLAIR CSF enhancement is associated with higher age and brain atrophy. • There is large methodological heterogeneity between studies that use this technique. • We provide recommendations for future methodological standardization.

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