Open AccessMultivariate neuroanatomical correlates of behavioral and psychological symptoms in dementia and the moderating role of education
Author(s) -
Seyul Kwak,
Soowon Park,
Jeongsim Kim,
Seho Park,
Jun-Young Lee
Publication year - 2020
Publication title -
neuroimage. clinical
Language(s) - English
Resource type - Journals
ISSN - 2213-1582
DOI - 10.1016/j.nicl.2020.102452
Subject(s) - dementia , psychology , mood , cognition , neuroimaging , clinical psychology , multivariate analysis , brain size , audiology , disease , psychiatry , medicine , magnetic resonance imaging , radiology
Highlights • Neuropsychiatric symptoms (NPS) in dementia includes aberrant behavior and mood changes.• The buffering role of cognitive reserve has been unclear in NPS.• Open Access Series of Imaging Studies (OASIS-3) dataset was utilized.• Canonical correlation analysis identified multivariate patterns of NPS correlate.• Older adults with more educational attainment showed minimal NPS.