Gait initiation in progressive supranuclear palsy: brain metabolic correlates
Author(s) -
Chiara Palmisano,
Massimiliano Todisco,
Giorgio Marotta,
Jens Volkmann,
Claudio Pacchetti,
C. Frigo,
Gianni Pezzoli,
Ioannis U. Isaias
Publication year - 2020
Publication title -
neuroimage clinical
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.772
H-Index - 68
ISSN - 2213-1582
DOI - 10.1016/j.nicl.2020.102408
Subject(s) - progressive supranuclear palsy , gait , physical medicine and rehabilitation , medicine , neuroscience , psychology , disease
Highlights • Dysfunctional gait initiation in progressive supranuclear palsy relates to poor feedforward motor control.• Hypometabolism of the caudate nucleus impairs programming of anticipatory postural adjustments.• Thalamic hypometabolism correlates with the center of mass kinematic resultants of anticipatory postural adjustments.
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