Hurdles on the road to personalized medicine | Zendy

Tursz Thomas | Zendy; Bernards Rene | Zendy

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Hurdles on the road to personalized medicine

Author(s) -

Tursz Thomas,

Bernards Rene

Publication year - 2015

Publication title -

molecular oncology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.332

H-Index - 88

eISSN - 1878-0261

pISSN - 1574-7891

DOI - 10.1016/j.molonc.2014.08.009

Subject(s) - personalized medicine , medicine , precision medicine , intensive care medicine , bioinformatics , biology , pathology

Cancer treatment is slowly shifting from an approach in which the tissue of origin and the histology were the guiding principles for the choice of chemotherapy towards a genotype‐centric approach in which the changes in the cancer genome are used to select patients for treatment with highly selective and targeted drugs. This transition has all the hallmarks of a disruptive innovation and requires major adjustments in the way that cancer is diagnosed and treated. We discuss here the hurdles on the road ahead to a more personalized treatment of cancer.

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