Open AccessIntracytoplasmic sperm injection in male renal transplant recipients
Author(s) -
Murat Berkkanoğlu,
Hasan Bulut,
Kevin Coetzee,
Kemal Özgür
Publication year - 2015
Publication title -
middle east fertility society journal/middle east fertility society journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.322
H-Index - 18
eISSN - 2090-3251
pISSN - 1110-5690
DOI - 10.1016/j.mefs.2014.10.002
Subject(s) - intracytoplasmic sperm injection , urology , medicine , andrology , renal transplant , sperm , biology , kidney , in vitro fertilisation , embryo , microbiology and biotechnology
Objective: In this study, we reviewed the reproductive outcomes following ICSI in 5 couples where the male partners had undergone renal transplantations. Chronic renal failure and dialysis may adversely affect male reproductive function resulting in severely depressed semen parameters or even azoospermia, which maybe further adversely affected by the immunosuppression taken from after transplantation.Study design: Case report.Setting: A private fertility clinic.Patients: The study included five infertile couples where the male partners were the recipients of renal transplants, 3–15 years prior to having ICSI treatment. All couples suffered from male factor infertility, with diagnoses of; azoospermia, asthenoteratozoospermia, oligoasthenoteratozoopsermia.Results: In the 5 case reports 5 ICSI and 3 FET treatment procedures were completed. In all but one of the cases grade 1 quality embryos were obtained and transferred. From the 8 embryo transfers performed 4 pregnancies were obtained, one miscarried at 8 weeks and 3 resulted in live births.Conclusions: In this study, we showed that pregnancy and normal live birth were possible following ICSI treatment for male factor infertility, where male partners had had renal transplants and were under immunosuppressive therapy