Open AccessValue of endometrial dyeing in diagnosis of endometritis in the absence of macroscopic abnormalities during hysteroscopy
Author(s) -
Hoda Mansour,
Mohamed A. Mohamed
Publication year - 2011
Publication title -
middle east fertility society journal/middle east fertility society journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.322
H-Index - 18
eISSN - 2090-3251
pISSN - 1110-5690
DOI - 10.1016/j.mefs.2010.09.006
Subject(s) - endometritis , hysteroscopy , dyeing , medicine , value (mathematics) , obstetrics , gynecology , mathematics , biology , pregnancy , chemistry , statistics , genetics , organic chemistry
Objective: To evaluate endometrial dyeing with methylene blue dye during hysteroscopy in diagnosis of endometritis.Design: Prospective cohort study.Materials and methods: The study included 57 patients with absent macroscopic pathology on transvaginal sonography and hysteroscopy. Endometrial features were described after methylene blue dye injection at hysteroscopy. Patients were classified into two groups. Group I (n=41) with diffuse light staining and Group II (n=16) with focal dark blue staining. Endometrial biopsy was then taken for histopathological examination.Results: There was a significant difference in diagnosis of chronic endometritis between both groups. Group I 3/41 (7.31%) and Group II 7/16 (43.57%) and P value was <0.05 in comparing both groups. Group II showed sensitivity (70%), specificity (80.8%), positive predictive value (43.7%) and negative predictive value (92.6%).Conclusion: Endometrial dyeing with methylene blue dye is a valuable tool at hysteroscopy for diagnosis of chronic endometritis and should be applied to such cases