Open AccessThe importance of MTHFR C677T/A1298C combined polymorphisms in pulmonary embolism in Turkish population
Author(s) -
Nurşah Başol,
Nevin Karakuş,
Aslı Yasemen Savas,
İlker Kaya,
Kayhan Karakuş,
Serbülent Yığıt
Publication year - 2016
Publication title -
medicina
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.104
H-Index - 10
eISSN - 1648-9144
pISSN - 1010-660X
DOI - 10.1016/j.medici.2016.01.003
Subject(s) - methylenetetrahydrofolate reductase , turkish population , medicine , gastroenterology , allele , population , allele frequency , pulmonary embolism , genetics , genotype , biology , gene , environmental health
Pulmonary embolism (PE) is an important cardiovascular emergency with high mortality. There are still problems related to the diagnosis of PE and genetic research may play a key role on diagnosis as well as determining risk stratification. In the present study, the aim was to evaluate MTHFR C677T and A1298C polymorphisms that play a role on folate metabolism in PE patients.