Open AccessNasopharyngeal carcinoma with pericardial metastasis
Author(s) -
Chen ShangWen,
Chen ChaoHsun,
Tsao ChaoJung,
Huang WenTsung,
Chuang ShihSung
Publication year - 2011
Publication title -
the kaohsiung journal of medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.439
H-Index - 36
eISSN - 2410-8650
pISSN - 1607-551X
DOI - 10.1016/j.kjms.2010.08.005
Subject(s) - medicine , pericardium , pericardial effusion , metastasis , nasopharyngeal carcinoma , pathology , biopsy , radiology , radiation therapy , cancer
Nasopharyngeal carcinoma (NPC) is prevalent in Taiwan and is characterized by a high frequency of nodal metastasis. The most common organs with distal metastases are the bones, lungs, and liver, with extremely rare cases to the pericardium. Herein, we report a rare case with NPC who presented with dyspnea and orthopnea. Serial studies, including pericardial biopsy, revealed NPC with pericardial metastasis and pericardial effusion. The tumor cells of both the original and metastatic tumors were positive for Epstein–Barr virus by in situ hybridization. This is the first histologically confirmed case of NPC with pericardial metastasis.