Urinary citrate: helpful to predict acid retention in CKD patients? | Zendy

Caroline ProtBertoye | Zendy; Marion Vallet | Zendy; Pascal Houillier | Zendy

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Urinary citrate: helpful to predict acid retention in CKD patients?

Author(s) -

Caroline ProtBertoye,

Marion Vallet,

Pascal Houillier

Publication year - 2019

Publication title -

kidney international

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.499

H-Index - 276

eISSN - 1523-1755

pISSN - 0085-2538

DOI - 10.1016/j.kint.2019.01.019

Subject(s) - urology , urinary system , medicine , citric acid , chemistry , biochemistry

Acid retention occurs early during the course of chronic kidney disease (CKD). Studies conducted in patients with CKD suggest that alkali supplementation may slow CKD progression. However, the diagnosis of acid retention is challenging when plasma bicarbonate concentration is still normal. In this issue, Goraya et al. suggest that urinary citrate may predict acid retention in eubicarbonatemic patients with stages 1 and 2 CKD . Although interesting, this claim yet requires confirmation by further studies.

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