Potential relevance of shear stress for slit diaphragm and podocyte function | Zendy

Wilhelm Kriz | Zendy; Kevin V. Lemley | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Potential relevance of shear stress for slit diaphragm and podocyte function

Author(s) -

Wilhelm Kriz,

Kevin V. Lemley

Publication year - 2017

Publication title -

kidney international

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.499

H-Index - 276

eISSN - 1523-1755

pISSN - 0085-2538

DOI - 10.1016/j.kint.2017.02.032

Subject(s) - slit diaphragm , podocyte , slit , shear (geology) , glomerular basement membrane , diaphragm (acoustics) , shear stress , materials science , basement membrane , anatomy , composite material , glomerulonephritis , optics , medicine , physics , proteinuria , kidney , acoustics , loudspeaker

Filtrate flow through the glomerular barrier produces shear stresses that tend to disconnect podocytes from the glomerular basement membrane. Forces are highest within the filtration slits. The slit diaphragm mechanically balances the lateral components of the shear stresses on opposing foot processes, preventing widening of the slit.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research