Bone strength: more than just bone density | Zendy

Susan M. Ott | Zendy

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Bone strength: more than just bone density

Author(s) -

Susan M. Ott

Publication year - 2016

Publication title -

kidney international

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.499

H-Index - 276

eISSN - 1523-1755

pISSN - 0085-2538

DOI - 10.1016/j.kint.2015.11.004

Subject(s) - medicine , kidney disease , bone density , raloxifene , bone marrow , bone healing , bone mineral , osteoporosis , dentistry , surgery , cancer , estrogen receptor , breast cancer

The following bone density measurements have limited utility in determining bone strength because they do not include bone quality: microarchitecture, mineralization, ability to repair damage, collagen structure, crystal size, or marrow composition. Patients with kidney disease have poor bone quality. Newman et al. now describe beneficial effects with raloxifene in an animal model of progressive kidney disease. These biomechanical measurements will be important in the development of medications to decrease fractures in patients.

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