Temporal expression of cytokines and B-cell phenotypes during mechanical circulatory support | Zendy

Amit Iyengar | Zendy; Nicholas Wisniewski | Zendy; Oh Jin Kwon | Zendy; Martín Cadeiras | Zendy; Mario C. Deng | Zendy; Joanna Schaenman | Zendy; Yael Korin | Zendy; Richard J. Shemin | Zendy; Elaine F. Reed | Zendy; Murray Kwon | Zendy

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Temporal expression of cytokines and B-cell phenotypes during mechanical circulatory support

Author(s) -

Amit Iyengar,

Nicholas Wisniewski,

Oh Jin Kwon,

Martín Cadeiras,

Mario C. Deng,

Joanna Schaenman,

Yael Korin,

Richard J. Shemin,

Elaine F. Reed,

Murray Kwon

Publication year - 2019

Publication title -

journal of thoracic and cardiovascular surgery

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.458

H-Index - 192

eISSN - 1085-8687

pISSN - 0022-5223

DOI - 10.1016/j.jtcvs.2019.03.061

Subject(s) - medicine , population , cytokine , antibody , immune system , immunophenotyping , circulatory system , immunology , interleukin 6 , inflammation , antigen , environmental health

Allosensitization during mechanical circulatory support (MCS) is a well-described phenomenon, although its mechanism remains unknown. Although immune-mediated interactions from devices or blood transfusions have been proposed, the role of inflammation in this development is less clear. This study was undertaken to further investigate the temporal association of cytokines and B-cell phenotypes in the MCS population.

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