Repair of naphthalene-induced acute tracheal injury by basal cells depends on β-catenin
Author(s) -
HanShui Hsu,
ChenChi Liu,
Jiun-Han Lin,
Tien-Wei Hsu,
Kelly Su,
ShihChieh Hung
Publication year - 2013
Publication title -
journal of thoracic and cardiovascular surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.458
H-Index - 192
eISSN - 1085-8687
pISSN - 0022-5223
DOI - 10.1016/j.jtcvs.2013.10.039
Subject(s) - wnt signaling pathway , respiratory epithelium , epithelium , stem cell , microbiology and biotechnology , biology , immunohistochemistry , basal (medicine) , pathology , medicine , immunology , endocrinology , signal transduction , insulin
Little is known about the role of Wnt/β-catenin in postnatal airway homeostasis and basal cell function. This study aimed to investigate the role of Wnt signaling in the self-renewal of basal cells and the involvement of β-catenin in tracheal repair after naphthalene-induced injury.
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