Pulmonary vein stenosis and the pathophysiology of “upstream” pulmonary veins | Zendy

Hideyuki Kato | Zendy; Yaqin Yana Fu | Zendy; Jiaquan Zhu | Zendy; Lixing Wang | Zendy; Shabana Aafaqi | Zendy; Otto Rahkonen | Zendy; Cameron Slorach | Zendy; Alexandra Traister | Zendy; Chung Ho Leung | Zendy; David A. Chiasson | Zendy; Luc Mertens | Zendy; Lee Benson | Zendy; Richard D. Weisel | Zendy; Boris Hinz | Zendy; Jason T. Maynes | Zendy; John G. Coles | Zendy; Christopher A. Caldarone | Zendy

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Pulmonary vein stenosis and the pathophysiology of “upstream” pulmonary veins

Author(s) -

Hideyuki Kato,

Yaqin Yana Fu,

Jiaquan Zhu,

Lixing Wang,

Shabana Aafaqi,

Otto Rahkonen,

Cameron Slorach,

Alexandra Traister,

Chung Ho Leung,

David A. Chiasson,

Luc Mertens,

Lee Benson,

Richard D. Weisel,

Boris Hinz,

Jason T. Maynes,

John G. Coles,

Christopher A. Caldarone

Publication year - 2013

Publication title -

journal of thoracic and cardiovascular surgery

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.458

H-Index - 192

eISSN - 1085-8687

pISSN - 0022-5223

DOI - 10.1016/j.jtcvs.2013.08.046

Subject(s) - medicine , pulmonary vein stenosis , pulmonary vein , vein , restenosis , umbilical vein , pathology , lung , stenosis , stent , cardiology , in vitro , biochemistry , chemistry , ablation

Surgical and catheter-based interventions on pulmonary veins are associated with pulmonary vein stenosis (PVS), which can progress diffusely through the "upstream" pulmonary veins. The mechanism has been rarely studied. We used a porcine model of PVS to assess disease progression with emphasis on the potential role of endothelial-mesenchymal transition (EndMT).

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