Virus infection-induced host mRNA degradation and potential application of live cell imaging
Author(s) -
Dan Qi,
Jitian Guan,
Erxi Wu
Publication year - 2018
Publication title -
radiology of infectious diseases
Language(s) - English
Resource type - Journals
eISSN - 2352-622X
pISSN - 2352-6211
DOI - 10.1016/j.jrid.2018.12.002
Subject(s) - host (biology) , virus , immune system , rna , biology , live cell imaging , virology , cell , immunology , gene , genetics
Viruses exist wherever there is life. They can cause allergy, immune response, inflammation, and even fatal diseases directly or indirectly. Accumulating evidence shows that host RNA undergoes rapid degradation during virus infection. Herein, we focus on several possible mechanisms of infection-induced host RNA turnover, which seems to be a common strategy for both prokaryotic and eukaryotic viruses during the very early stage of infection and a potential application of live cell imaging on its visualization.
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