Antibiotic containing bone cement in prevention of hip and knee prosthetic joint infections: A systematic review and meta-analysis | Zendy

Sujeesh Sebastian | Zendy; Yang Liu | Zendy; Robin Christensen | Zendy; Deepak Raina | Zendy; Magnus Tägil | Zendy; Lars Lidgren | Zendy

Open Access

Antibiotic containing bone cement in prevention of hip and knee prosthetic joint infections: A systematic review and meta-analysis

Author(s) -

Sujeesh Sebastian,

Yang Liu,

Robin Christensen,

Deepak Raina,

Magnus Tägil,

Lars Lidgren

Publication year - 2020

Publication title -

journal of orthopaedic translation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.128

H-Index - 26

eISSN - 2214-0328

pISSN - 2214-031X

DOI - 10.1016/j.jot.2020.04.005

Subject(s) - bone cement , meta analysis , medicine , cement , joint (building) , joint infections , knee joint , dentistry , surgery , arthroplasty , materials science , engineering , composite material , architectural engineering , periprosthetic

Prosthetic joint infection (PJI) is the most serious total joint arthroplasty (TJA) complication despite several aseptic and antiseptic preventive measures. There is no clear evidence or even consensus, whether antibiotic-loaded bone cement (ALBC) should be used, in addition to systemic short-term routine antibiotic prophylaxis, to reduce the risk of PJI in primary TJA. We aimed to analyze the efficacy of ALBC for prevention of PJI in patients undergoing primary TJA.

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