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Analysis of the clinical symptoms of patients complicated with acute intestinal obstruction after the surgery of colon cancer
Author(s) -
Pei-Jun Ye
Publication year - 2016
Publication title -
journal of acute disease
Language(s) - English
Resource type - Journals
eISSN - 2589-5516
pISSN - 2221-6189
DOI - 10.1016/j.joad.2016.08.012
Subject(s) - medicine , procalcitonin , ileus , gastroenterology , colorectal cancer , tumor necrosis factor alpha , postoperative ileus , interleukin 6 , cancer , surgery , c reactive protein , colonic cancer , inflammation , sepsis
Objective: To study the content of serum inflammatory medium of the patients\udcomplicated with acute intestinal obstruction after the surgery of colon cancer.\udMethods: A total of 150 patients with colon cancer received limited surgery treatment\udduring the period of May 2012 to October 2015 were selected as the study objects. They\udwere divided into postoperative ileus (POI) group and non-postoperative ileus (non-POI)\udgroup according to the presence or absence of intestinal obstruction. Then, the contents of\udserum procalcitonin (PCT), C-reactive protein (CRP), tumor necrosis factor-alpha (TNFa) and interleukin-6 (IL-6) were detected at the 1st, 3rd, 5th and 7th days after the\udsurgery.\udResults: The levels of serum PCT, CRP, TNF-a and IL-6 of two groups at the 1st day\udhad no differences after the surgery. The level of serum PCT of POI group tended to\udincrease and its levels of serum CRP, TNF-a and IL-6 tended to decrease at the 3rd, 5th\udand 7th days after the surgery, while the levels of serum PCT, CRP, TNF-a and IL-6 of\udnon-POI group were decreased. The content of serum PCT of POI group and non-POI\udgroup at the 3rd day after the surgery had no differences (P > 0.05), and the level of\udserum PCT of POI group was higher than that of non-POI group at the 5th and 7th days\udafter the surgery (P < 0.05). The levels of serum CRP, TNF-a and IL-6 of POI group and\udnon-POI group had no differences at the 3rd, 5th and 7th days after the surgery\ud(P > 0.05).\udConclusions: The raising of the content of serum PCT after the surgery can be used as\udthe laboratory index to predict the incidence of acute intestinal obstruction after the\udsurgery of colon cancer.\ud1. Introduction\udPostoperative ileus (POI) mainly happens after major\udabdominal surgeries causing the clinical symptoms such as\udabdominal pain, abdominal distension, no flatus and defecation,\udetc. Colorectal cancer is a common malignant tumor in the\uddigestive system, and the incidence and death rates of the disease\udwere all tending to i

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