Open AccessDetection of neutrophil–lymphocyte ratio as a serum marker associated with inflammations by acute carbon monoxide poisoning
Author(s) -
Mustafa Karabacak,
Kenan Ahmet Türkdoğan,
Abuzer Coşkun,
Orhan Akpınar,
Ali Duman,
Mücahit Kapçı,
Şevki Hakan Eren,
Pınar Karabacak
Publication year - 2015
Publication title -
journal of acute disease
Language(s) - English
Resource type - Journals
eISSN - 2589-5516
pISSN - 2221-6189
DOI - 10.1016/j.joad.2015.06.009
Subject(s) - medicine , carbon monoxide poisoning , white blood cell , neutrophil to lymphocyte ratio , gastroenterology , lymphocyte , platelet , co poisoning , absolute neutrophil count , systemic inflammation , immunology , inflammation , toxicity , poison control , neutropenia , biochemistry , chemistry , environmental health , catalysis
ObjectiveTo investigate neutrophil–lymphocyte ratio (NLR), which is an indicator of systemic inflammation, in patients with carbon monoxide (CO) poisoning.MethodsWe included 528 patients (275 women) who presented with a diagnosis of CO poisoning between June 2009 and March 2014. Control group was composed of 54 patients (24 women). Platelet count and mean platelet volume level were significantly higher in the CO poisoning group.ResultsWhite blood cell level (9.8 ± 3.3 vs. 8.6 ± 2.9 × 103/mL, respectively; P = 0.01), neutrophil count (6.00 ± 2.29 vs. 4.43 ± 2.04 × 103/mL, respectively; P < 0.01) and NLR (3.01 ± 2.34 vs. 2.23 ± 1.27, respectively; P = 0.02) were significantly higher in CO poisoning group.ConclusionsThe increase of NLR may indicate the progression of fatal complications due to CO poisoning