Open AccessIschemic Brugada phenocopy during ablation of ventricular tachycardia
Author(s) -
Gottschalk Byron H.,
Anselm Daniel D.,
Baranchuk Adrian
Publication year - 2016
Publication title -
journal of arrhythmia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.463
H-Index - 21
eISSN - 1883-2148
pISSN - 1880-4276
DOI - 10.1016/j.joa.2015.11.002
Subject(s) - medicine , cardiology , phenocopy , brugada syndrome , ventricular tachycardia , catheter ablation , context (archaeology) , coronary artery disease , ablation , paleontology , biochemistry , chemistry , biology , mutant , gene
We examined the report by Hori et al. with specific interest in their description of a Brugada ECG (electrocardiogram) pattern observed during ablation of ventricular tachycardia (VT) [1]. Their case provides an important contribution to an expanding database of ischemic Brugada phenocopies (BrP) [2], [3].BrP are characterized by ECG patterns identical to those of Brugada syndrome (BrS), but are elicited under various circumstances [2], [3]. They are classified according to six etiological categories: (i) metabolic conditions; (ii) mechanical compression; (iii) myocardial ischemia u0026 pulmonary embolism; (iv) myocardial u0026 pericardial disease; (v) ECG modulations; and (vi) miscellaneous. See www.brugadaphenocopy.com.The authors [1] presented the case of a 63-year-old man undergoing catheter ablation of ischemic VT. The patient developed a Type-1 Brugada ECG pattern during the procedure, resolving upon observation within two minutes. During this time, the mapping catheter appeared to have been pushed against the left ventricular wall. The patient was subjected to provocative testing with pilsicainide, the results of which were negative.We believe that this patient developed BrP in the context of ischemia, resulting from direct compression of a coronary artery or vasospasm. Ischemic causes of BrP are not uncommon; however, this is the first confirmed case to observe a BrP during ablation of VT [4], [5].This case has been included in our database as a Type-1A BrP, under the category of myocardial and pericardial disease.