Open AccessSupraventricular tachyarrhythmia in patients with Brugada syndrome: A single‐center study
Author(s) -
Ohkubo Kimie,
Watanabe Ichiro,
Okumura Yasuo,
Kofune Masayoshi,
Nagashima Koichi,
Mano Hiroaki,
Sonoda Kazumasa,
Nakai Toshiko,
Kunimoto Satoshi,
Kasamaki Yuji,
Hirayama Atsushi,
Sumitomo Naokata,
Nakayama Tomohiro
Publication year - 2013
Publication title -
journal of arrhythmia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.463
H-Index - 21
eISSN - 1883-2148
pISSN - 1880-4276
DOI - 10.1016/j.joa.2013.01.014
Subject(s) - medicine , brugada syndrome , cardiology , atrioventricular reentrant tachycardia , supraventricular arrhythmia , presyncope , supraventricular tachycardia , atrial fibrillation , sudden cardiac death , palpitations , sudden death , tachycardia , accessory pathway , catheter ablation , heart rate , blood pressure
Background Brugada syndrome is a distinct form of idiopathic ventricular fibrillation. We retrospectively investigated the incidence and clinical implications of supraventricular tachyarrhythmia in patients with Brugada syndrome. Methods We reviewed 69 consecutive cases of Brugada syndrome, 11 of which had a history of syncope. Results Seven patients (10.1%) had clinically documented supraventricular tachyarrhythmia: 3 patients with atrioventricular reentrant tachycardia, 2 with atrioventricular nodal reentrant tachycardia, and 2 with paroxysmal atrial fibrillation. The prevalence of a spontaneous type 1 Brugada electrocardiogram and symptoms (history of syncope, presyncope, documented ventricular tachyarrhythmia, or aborted sudden cardiac death) were significantly higher, and QRS duration was significantly longer in patients without than in those with supraventricular tachyarrhythmia. The PR and AH intervals were also longer in patients without than in those with supraventricular tachyarrhythmia, but the differences were not statistically significant. Conclusion The arrhythmogenic substrate in Brugada syndrome may not be restricted to the ventricles. Palpitations in patients with this syndrome should raise the question of supraventricular tachyarrhythmia. Conversely, in patients with supraventricular tachyarrhythmia and aborted sudden cardiac death or syncope not related to supraventricular tachyarrhythmia, Brugada syndrome should be considered a possible additional electrophysiologic abnormality.