Open AccessLaryngeal synovial sarcoma: Report of 2 cases
Author(s) -
Mouna Bellakhdhar,
Amira Cheniti,
Monia Ghammem,
Ahlem Bdioui,
S Mestiri,
Meherzi Abir,
Wassim Kermani,
Mohamed Abdelkéfi
Publication year - 2018
Publication title -
journal of egyptian national cancer institute/journal of the egyptian national cancer institute
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.398
H-Index - 22
eISSN - 2589-0409
pISSN - 1110-0362
DOI - 10.1016/j.jnci.2018.10.002
Subject(s) - medicine , larynx , synovial sarcoma , malignancy , laryngectomy , sarcoma , biopsy , radiation therapy , radiology , surgery , pathology
Synovial sarcoma is a malignant mesenchymal tumor. It most commonly occurs in the lower extremities of young adults. The head and neck are rare sites, accounting for less than 10%. The larynx is an extremely rare site. We report two cases of 27 and 18 year-old men who developed a synovial sarcoma of the larynx. They presented with hoarseness of voice and hemoptysis. Endoscopy detected a mass in the supraglottic region. The biopsy concluded a synovial sarcoma. Immunohistochemistry conveyed diagnostic certainty. They had been treated with total laryngectomy and post-operative radiotherapy. The 2 patients are seen for regular follow-ups in our department and they remained recurrence-free for 10 years and 24 months, respectively. Synovial sarcoma is a very rare tumor of the larynx. A multidisciplinary therapeutic approach is essential for the management of this malignancy. Long-term follow-up is required to monitor for recurrence and improve disease-free survival.